All functions |
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Calculate the adjacency matrix given a spatial coordinate matrix |
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Add FAST model settings for a PRECASTObj object |
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Calculate UMAP projections for coembedding of cells and features |
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Coembedding dimensional reduction plot |
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A Seurat object including spatial transcriptomics dataset from CosMx platform |
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Determine the dimension of low dimensional embedding |
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Run FAST model for a PRECASTObj object |
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(Varitional) ICM-EM algorithm for implementing FAST model |
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Fit FAST model for single-section SRT data |
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(Varitional) ICM-EM algorithm for implementing FAST model with structurized parameters |
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Find the signature genes for each group of cell/spots |
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Obtain the top signature genes and related information |
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Calcuate the the adjusted McFadden's pseudo R-square |
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Integrate multiple SRT data into a Seurat object |
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Fit an iSC-MEB model using specified multi-section embeddings |
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Set parameters for FAST model |
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Cell-feature coembedding for scRNA-seq data |
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Cell-feature coembedding for SRT data |
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A Seurat object including scRNA-seq PBMC dataset |
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Calculate the cell-feature distance matrix |
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Embedding alignment and clustering based on the embeddings from FAST |
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Fit an iSC-MEB model using the embeddings from FAST |
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Select housekeeping genes |
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A data.frame object including top five signature genes in scRNA-seq PBMC dataset |
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Transfer gene names from one fortmat to the other format |